Microdeposits of amyloid in sclerocalcific heart valves: a histochemical and immunofluorescence study.

Incidence and origin of non-systemic microdeposits of amyloid.

In a general hospital, 391 consecutive necropsies in which at least seven organs were available, were examined retrospectively by polarizing microscopy of Congo-red-stained sections for the presence of local amyloid deposits.Non-systemic microdeposits of amyloid were encountered in 72 cases, an overall incidence of 18.4%. They were usually small and frequently detectable only by virtue of polar...

نقش گیرنده‌های نیکوتینی استیل کولین، پروتئین کیناز B و پروتئین کیناز Mζ بر اثر حفاظتی اسید رزمارینیک در مدل بیماری آلزایمر القا شده به وسیله‌ی بتا آمیلوئید (35-25) در موش صحرایی

Background and Objective: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and results from the extracellular accumulation of b-amyloid peptides and the resulting neuronal dysfunction. In this study, the role of nicotinic acetylcholine receptors, protein kinase B (PKB) and protein kinase M (PKM) were evaluated in order to examine the mechanism of the protective effe...

Anti-Coagulation During Pregnancy in Women with Mechanical Heart Valves: A Prospective Study

Pregnancy Outcome with Intracytoplasmic Sperm Injection Method in a Woman with Prosthetic Heart Valves

There is an increased risk of thromboembolism, anticoagulant-related hemorrhage, fetal-wastage and congestive cardiac failure in pregnant women with mechanical heart valves. In order to have a good outcome, the care of such patients must necessarily be multidisciplinary and in a well- equipped centre with adequate support services .One such patient who had mechanical mitral and aortic valves re...

A survey on the prevalence of heart murmurs in polo horses

Background: Cardiac murmur and subsequently cardiac failure is one of the poor-performance causes in athletic horses. Attention to murmur character is vital during heart examination. Polo is a sport which demands very high stress on horses, which may result in more stress on cardiovascular system. Objectives: In this study we assume that high pressure on polo horses makes them more susceptible ...